TTD | Drug: D0M7TW

Drug General Information
Drug ID	D0M7TW
Former ID	DIB012289
Drug Name	PF-3900422
Synonyms	PF-03900422; Histamine H3 receptor antagonist (central nervous system disease), Pfizer
Indication	Central nervous system disease [ICD10:G00-G99]		Investigative	[543673]
Company	Pfizer Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C(=O)(c1cc(ccc1)c1cc2c(cc1)CC(CC2)N1CCCC1)N(C)CC
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Antagonist	[543673]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543673	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).
Ref 543673	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).

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Drug Information