Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0M8SY
|
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| Former ID |
DIB019291
|
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| Drug Name |
compound 18b
|
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| Drug Type |
Small molecular drug
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C35H46ClN5O3
|
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| InChI |
InChI=1S/C35H45N5O3.ClH/c1-9-10-17-40-33-27(15-12-16-36-33)30(25-13-11-14-26(20-25)43-8)32(34(40)41)38-35(42)37-31-28(22(2)3)18-24(21-39(6)7)19-29(31)23(4)5;/h11-16,18-20,22-23H,9-10,17,21H2,1-8H3,(H2,37,38,42);1H
|
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| InChIKey |
YCGQPIRMLGEWMW-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Acetyl-CoA acetyltransferase, mitochondrial | Target Info | Inhibitor | [527814] | |
| KEGG Pathway | Fatty acid degradation | ||||
| Synthesis and degradation of ketone bodies | |||||
| Valine, leucine and isoleucine degradation | |||||
| Lysine degradation | |||||
| Tryptophan metabolism | |||||
| Pyruvate metabolism | |||||
| Glyoxylate and dicarboxylate metabolism | |||||
| Propanoate metabolism | |||||
| Butanoate metabolism | |||||
| Terpenoid backbone biosynthesis | |||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| Carbon metabolism | |||||
| Fatty acid metabolism | |||||
| NetPath Pathway | Leptin Signaling Pathway | ||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| References | |||||
| Ref 527814 | Bioorg Med Chem Lett. 2006 Jan 1;16(1):44-8. Epub 2005 Oct 18.Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)-on-3-yl ureas: potent acyl-CoA:cholesterol acyltransferase inhibitor with improved aqueous solubility. | ||||
| Ref 541829 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6728). | ||||
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