Drug General Information
Drug ID
D0N7KK
Former ID
DNC008236
Drug Name
5-methoxy-2-(2-(pyrrolidin-1-yl)ethyl)-1H-indole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529212]
Structure
Download
2D MOL

3D MOL

Formula
C15H20N2O
Canonical SMILES
COC1=CC2=C(C=C1)NC(=C2)CCN3CCCC3
InChI
1S/C15H20N2O/c1-18-14-4-5-15-12(11-14)10-13(16-15)6-9-17-7-2-3-8-17/h4-5,10-11,16H,2-3,6-9H2,1H3
InChIKey
UXDACHZONACAIV-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [529212]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529212Bioorg Med Chem Lett. 2008 Jan 1;18(1):355-9. Epub 2007 Oct 24.In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series.
Ref 529212Bioorg Med Chem Lett. 2008 Jan 1;18(1):355-9. Epub 2007 Oct 24.In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series.

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