Drug Information
Drug General Information | |||||
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Drug ID |
D0N8QK
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Former ID |
DNCL001986
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Drug Name |
ABT-288
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Drug Type |
Small molecular drug
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Company |
Abbott Laboratories
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Structure |
Download2D MOL |
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Formula |
C23H24N4O
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InChI |
InChI=1S/C23H24N4O/c1-25-15-19-12-14-26(22(19)16-25)20-8-4-17(5-9-20)18-6-10-21(11-7-18)27-23(28)3-2-13-24-27/h2-11,13,19,22H,12,14-16H2,1H3/t19-,22+/m1/s1
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InChIKey |
GNIRITULTPTAQW-KNQAVFIVSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Histamine H3 receptor | Target Info | Modulator | ||
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
References | |||||
Ref 522864 | ClinicalTrials.gov (NCT01018875) Efficacy and Safety Study of ABT-288 in Subjects With Mild-to-Moderate Alzheimer's Disease. U.S. National Institutes of Health. | ||||
Ref 541972 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6927). |
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