Drug Information

Drug General Information
Drug ID
D0O5ZB
Former ID
DIB004110
Drug Name
Ilodecakin
Synonyms
Prevascar; Ilodecakin, Renovo; Recombinant IL-10 (scarring), Renovo
Indication Scar tissue [ICD10:L00-L99] Phase 2 [522798]
Company
Renovo Group plc
CAS Number
CAS 149824-15-7
Target and Pathway
Target(s) Interleukin-10 Target Info Modulator [527700]
KEGG Pathway Cytokine-cytokine receptor interaction
FoxO signaling pathway
Jak-STAT signaling pathway
T cell receptor signaling pathway
Intestinal immune network for IgA production
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Toxoplasmosis
Amoebiasis
Staphylococcus aureus infection
Tuberculosis
Epstein-Barr virus infection
Asthma
Autoimmune thyroid disease
Inflammatory bowel disease (IBD)
Systemic lupus erythematosus
Allograft rejection
NetPath Pathway TCR Signaling Pathway
BCR Signaling Pathway
IL2 Signaling Pathway
IL4 Signaling Pathway
PANTHER Pathway Interleukin signaling pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
IL4-mediated signaling events
AP-1 transcription factor network
WikiPathways SIDS Susceptibility Pathways
Cytokines and Inflammatory Response
Allograft Rejection
References
Ref 522798ClinicalTrials.gov (NCT00984646) Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10). U.S. National Institutes of Health.
Ref 527700Ilodecakin. Schering-Plough Corp. IDrugs. 1999 Oct;2(10):1045-58.

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