TTD | Drug: D0OQ3L

Drug General Information
Drug ID	D0OQ3L
Former ID	DNC001342
Drug Name	SL65.0472
Drug Type	Small molecular drug
Indication	Cardiovascular disorder [ICD10:I00-I99]		Discontinued in Phase 2	[547242]
Structure		Download 2D MOL 3D MOL
Formula	C25H26FN5OS
Canonical SMILES	C=C1C=C(C2=C(N1CC(=O)N)C=C(C=C2)F)CCN3CCN(CC3)C4=NC=CC5<br />=C4C=CS5
InChI	1S/C25H26FN5OS/c1-17-14-18(20-3-2-19(26)15-22(20)31(17)16-24(27)32)5-8-29-9-11-30(12-10-29)25-21-6-13-33-23(21)4-7-28-25/h2-4,6-7,13-15H,1,5,8-12,16H2,(H2,27,32)
InChIKey	ZDPDWSUPGWKYLE-UHFFFAOYSA-N
PubChem Compound ID	56603793
PubChem Substance ID	134340538, 172080028
Target and Pathway
Target(s)	5-hydroxytryptamine 2A receptor	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and STAT3 Signaling
	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 547242	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014358)

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Drug Information