Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0P5UW
|
||||
Former ID |
DNC007165
|
||||
Drug Name |
ECOPLADIB
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Discovery agent | Investigative | [529940] | ||
Structure |
Download2D MOL |
||||
Formula |
C39H33Cl3N2O5S
|
||||
Canonical SMILES |
C1=CC=C(C=C1)C(C2=CC=CC=C2)N3C4=C(C=C(C=C4)Cl)C(=C3CCNS<br />(=O)(=O)CC5=CC(=C(C=C5)Cl)Cl)CCOC6=CC=C(C=C6)C(=O)O
|
||||
InChI |
1S/C39H33Cl3N2O5S/c40-30-14-18-36-33(24-30)32(20-22-49-31-15-12-29(13-16-31)39(45)46)37(19-21-43-50(47,48)25-26-11-17-34(41)35(42)23-26)44(36)38(27-7-3-1-4-8-27)28-9-5-2-6-10-28/h1-18,23-24,38,43H,19-22,25H2,(H,45,46)
|
||||
InChIKey |
FMMCHWHNSUBYAV-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Cytosolic phospholipase A2 | Target Info | Inhibitor | [529940] | |
BioCyc Pathway | Phospholipases | ||||
KEGG Pathway | Glycerophospholipid metabolism | ||||
Ether lipid metabolism | |||||
Arachidonic acid metabolism | |||||
Linoleic acid metabolism | |||||
alpha-Linolenic acid metabolism | |||||
Metabolic pathways | |||||
MAPK signaling pathway | |||||
Ras signaling pathway | |||||
Vascular smooth muscle contraction | |||||
VEGF signaling pathway | |||||
Platelet activation | |||||
Fc epsilon RI signaling pathway | |||||
Fc gamma R-mediated phagocytosis | |||||
Glutamatergic synapse | |||||
Serotonergic synapse | |||||
Long-term depression | |||||
Inflammatory mediator regulation of TRP channels | |||||
GnRH signaling pathway | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Choline metabolism in cancer | |||||
NetPath Pathway | TCR Signaling Pathway | ||||
Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
Endothelins | |||||
PDGFR-beta signaling pathway | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
PathWhiz Pathway | Fc Epsilon Receptor I Signaling in Mast Cells | ||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.