Drug Information

Drug General Information
Drug ID
D0P9LO
Former ID
DIB011760
Drug Name
BP-2.94
Synonyms
FUB-94; (-)-2-[1-[2-(4-Imidazolyl)-1(R)-methylethylimino]-1-phenylmethyl]phenol
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Discontinued in Phase 2 [546450]
Structure
Download
2D MOL

3D MOL
Formula
C19H19N3O
Canonical SMILES
CC(CC1=CN=CN1)NC(=C2C=CC=CC2=O)C3=CC=CC=C3
InChI
1S/C19H19N3O/c1-14(11-16-12-20-13-21-16)22-19(15-7-3-2-4-8-15)17-9-5-6-10-18(17)23/h2-10,12-14,22H,11H2,1H3,(H,20,21)/b19-17+
InChIKey
NDSIMLLWOSEGGX-HTXNQAPBSA-N
PubChem Compound ID
5487462
PubChem Substance ID
39473150, 53788309, 57364291, 80712782, 85210141, 113995131, 135088150, 137267150, 227838188
Target and Pathway
Target(s) Histamine H3 receptor Target Info Modulator [534203]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 546450Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008192)
Ref 534203Sleep and waking during acute histamine H3 agonist BP 2.94 or H3 antagonist carboperamide (MR 16155) administration in rats. Neuropsychopharmacology. 1996 Jul;15(1):31-5.

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