Drug Information
Drug General Information | |||||
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Drug ID |
D0R7XD
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Former ID |
DNCL002807
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Drug Name |
GSK1325756
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Drug Type |
Small molecular drug
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Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C19H21ClFN3O4S
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InChI |
InChI=1S/C19H21ClFN3O4S/c1-11-14(21)5-2-6-15(11)23-19(26)24-16-8-7-13(20)18(17(16)25)29(27,28)12-4-3-9-22-10-12/h2,5-8,12,22,25H,3-4,9-10H2,1H3,(H2,23,24,26)/t12-/m0/s1
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InChIKey |
NGYNBSHYFOFVLS-LBPRGKRZSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | High affinity interleukin-8 receptor B | Target Info | Modulator | [1572591] | |
NetPath Pathway | TNFalpha Signaling Pathway | ||||
Pathway Interaction Database | IL8- and CXCR2-mediated signaling events | ||||
References | |||||
Ref 525227 | ClinicalTrials.gov (NCT02469298) Safety, Tolerability and Clinical Effect of Danirixin in Adults With Influenza. | ||||
Ref 543174 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8500). |
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