Drug General Information
Drug ID
D0T1QV
Former ID
DNCL002941
Drug Name
ARA 290
Indication Depression; Diabetic neuropathy; Mood disorder [ICD9: 311, 250, 250.6, 356.0, 356.8; ICD10:F30-F39, E11.40] Phase 2 [549308]
Company
Araim Pharmaceuticals
Structure
Download
2D MOL
Target and Pathway
Target(s) Erythropoietin ligand Target Info Modulator
KEGG Pathway Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Pathway Interaction Database HIF-2-alpha transcription factor network
Signaling events mediated by Stem cell factor receptor (c-Kit)
EPO signaling pathway
HIF-1-alpha transcription factor network
Reactome Regulation of gene expression by Hypoxia-inducible Factor
WikiPathways EPO Receptor Signaling
Hematopoietic Stem Cell Differentiation
Differentiation Pathway
Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
References
Ref 549308Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035038)

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