Drug General Information
Drug ID	D0TF9R
Former ID	DNC007850
Drug Name	2-(o-toluidino)-5-isopropylthiazol-4(5H)-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529083]
Structure		Download 2D MOL 3D MOL
Formula	C13H16N2OS
Canonical SMILES	CC1=CC=CC=C1NC2=NC(=O)C(S2)C(C)C
InChI	1S/C13H16N2OS/c1-8(2)11-12(16)15-13(17-11)14-10-7-5-4-6-9(10)3/h4-8,11H,1-3H3,(H,14,15,16)
InChIKey	WTDVJQRSTXJXKV-UHFFFAOYSA-N
PubChem Compound ID	11708587
Target and Pathway
Target(s)	Corticosteroid 11-beta-dehydrogenase, isozyme 1	Target Info	Inhibitor	[529083]
KEGG Pathway	Steroid hormone biosynthesis
	Metabolism of xenobiotics by cytochrome P450
	Metabolic pathways
	Chemical carcinogenesis
NetPath Pathway	IL1 Signaling Pathway
	FSH Signaling Pathway
PathWhiz Pathway	Steroidogenesis
Reactome	Glucocorticoid biosynthesis
WikiPathways	Prostaglandin Synthesis and Regulation
	Metabolism of steroid hormones and vitamin D
	Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 529083	Bioorg Med Chem Lett. 2007 Nov 15;17(22):6056-61. Epub 2007 Sep 25.The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.
Ref 529083	Bioorg Med Chem Lett. 2007 Nov 15;17(22):6056-61. Epub 2007 Sep 25.The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.

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