Drug Information

Drug General Information
Drug ID
D0U0RZ
Former ID
DAP000719
Drug Name
Phentermine
Synonyms
Duromine; Fastin; Fentermina; Inoamin; Ionamin; Ionamine; Linyl; Lipopill; Lonamin; Mirapront; Normephentermine; Obenix; Obermine; Omnibex; Ortetamin; Ortetamina; Ortetaminum; Phentercot; Phenterminum; Phentride; Phentrol; Wilpo; Zantryl; Ona Mast; Ortetamine [INN]; Phentermine HCl; Phentermine resin complex; AmbkkkkK744; Phentermine Resin 30; Phentrol 2; Phentrol 3; Phentrol 4; Adipex P (TN); Adipex-P; Alpha-Benzylisopropylamine; Duromine (TN); Fastin (TN); Fentermina [INN-Spanish]; Ionamin (TN); Mirapront (TN); Obenix (TN); Obephen (TN); Obermine (TN); Oby-Trim; Panbesy (TN); Phenterex (TN); Phentermine (TN); Phenterminum [INN-Latin]; Phentremene (TN); Phentrol (TN); Phentromin (TN); Pro-Fast; Redusa (TN); Sinpet (TN); Supremin (TN); Teramine (TN); Trenker (TN); Umine (TN); Weltmine (TN); Zantryl (TN); Alpha,alpha-Dimethylbenzeneethanamine; Alpha,alpha-Dimethylphenethylamine; Anoxine-AM (TN); Obestin-30 (TN); Oby-Trim (TN); Phentermine (USAN/INN); Phentermine [USAN:INN:BAN]; Phenyl-tert-butylamine; Phenyl-tertiary-butylamine; Pro-Fast SA (TN); Alpha,alpha-Dimethyl-beta-phenylethylamine; Alpha.,.alpha.-dimethyl-Benzeneethanamine; (alpha,alpha)-Dimethylphenethylamine; 1,1-Dimethyl-2-phenylethylamine; 1-(2-Methylphenyl)-2-propylamin; 1-(2-Tolyl)-2-propylamine; 2-Amino-2-methyl-1-phenylpropane; 2-Methyl-1-phenyl-2-propanamine; 2-Phenyl-tert-butylamine; 2-methyl-1-phenylpropan-2-amine
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Approved [536710], [542288]
Therapeutic Class
Appetite Depressants
Company
Medeva Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C10H15N
InChI
InChI=1S/C10H15N/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7H,8,11H2,1-2H3
InChIKey
DHHVAGZRUROJKS-UHFFFAOYSA-N
CAS Number
CAS 122-09-8
PubChem Compound ID
4771
PubChem Substance ID
9642, 3222908, 4448495, 7980294, 8152931, 10505791, 15194700, 29223855, 43997956, 46508515, 47207127, 48416420, 49760715, 50004323, 50139243, 50429715, 57322442, 92307866, 103589701, 104101988, 104307379, 108670465, 119523660, 125309124, 126540999, 127734846, 134223805, 134338007, 134339372, 134973544, 137001247, 140204802, 144075901, 160963539, 163138806, 164205807, 170505704, 175266408, 176325847, 178103843, 179095233, 184574182, 184823557, 223787896, 226414425, 243694279, 249924131, 252324490
ChEBI ID
ChEBI:8080
SuperDrug ATC ID
A08AA01
SuperDrug CAS ID
cas=000100925
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Inhibitor [535068]
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 536710Anti-obesity drugs. Expert Opin Pharmacother. 2008 Jun;9(8):1339-50.
Ref 542288(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7269).
Ref 535068Novel anti-obesity drugs. Expert Opin Investig Drugs. 2000 Jun;9(6):1317-26.

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