Drug Information

Drug General Information
Drug ID
D0U5NA
Former ID
DIB020847
Drug Name
RP-69758
Synonyms
RP 69758
Drug Type
Small molecular drug
Indication Discovery agent Investigative [543297]
Structure
Download
2D MOL
Formula
C26H26N4O5
InChI
InChI=1S/C26H26N4O5/c1-29(21-11-4-2-5-12-21)24(32)18-30(22-13-6-3-7-14-22)23(31)17-27-26(35)28-20-10-8-9-19(15-20)16-25(33)34/h2-15H,16-18H2,1H3,(H,33,34)(H2,27,28,35)
InChIKey
CRUWRCOXWORZBA-UHFFFAOYSA-N
PubChem Compound ID
9847721
PubChem Substance ID
14809766, 24144480, 44945787, 74704067, 85213394, 127668699, 135650931, 234593171
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info Antagonist [533750]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPK
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 543297(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 906).
Ref 533750Pharmacological properties of ureido-acetamides, new potent and selective non-peptide CCKB/gastrin receptor antagonists. Eur J Pharmacol. 1994 Sep 12;262(3):233-45.

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