Drug General Information
Drug ID	D0UX4A
Former ID	DIB001674
Drug Name	HU-433
Synonyms	CB2 activator (osteoporosis); HU-433; CB2 activator (osteoporosis), Yissum
Indication	Osteoporosis [ICD9: 733.0, V07.4; ICD10:M80-M81, Z79.890]		Investigative	[543878]
Company	Yissum Research Development Co
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1(c(cc(cc1OC)C(CCCCCC)(C)C)OC)[C@@H]1C=C([C@H]2C(C)(C)<br />[C@@H]1C2)CO
Target and Pathway
Target(s)	Cannabinoid receptor 2	Target Info	Activator	[543878]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543878	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).
Ref 543878	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).

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