Drug Information

Drug General Information
Drug ID
D0V4XG
Former ID
DIB009852
Drug Name
GSK2793660
Synonyms
2793660
Indication Bronchiectasis [ICD9: 494, 748.61; ICD10:J47, Q33.4] Phase 1 [524641]
Company
Glaxosmithkline
Target and Pathway
Target(s) Dipeptidyl-peptidase I Target Info Modulator [524641]
KEGG Pathway Lysosome
NetPath Pathway IL2 Signaling Pathway
IL4 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
Reactome COPII (Coat Protein 2) Mediated Vesicle Transport
MHC class II antigen presentation
Cargo concentration in the ER
WikiPathways miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 524641ClinicalTrials.gov (NCT02058407) A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects. U.S. National Institutes of Health.
Ref 524641ClinicalTrials.gov (NCT02058407) A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects. U.S. National Institutes of Health.

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