Drug Information

Drug General Information
Drug ID
D0W6TX
Former ID
DNC008117
Drug Name
N-(4-iodophenyl)-4-(trifluoromethoxy)benzamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529233]
Structure
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2D MOL

3D MOL
Formula
C14H9F3INO2
Canonical SMILES
C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)I)OC(F)(F)F
InChI
1S/C14H9F3INO2/c15-14(16,17)21-12-7-1-9(2-8-12)13(20)19-11-5-3-10(18)4-6-11/h1-8H,(H,19,20)
InChIKey
IUHUCVXLTXIWPU-UHFFFAOYSA-N
PubChem Compound ID
7927254
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Inhibitor [529233]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 529233Bioorg Med Chem Lett. 2008 Feb 1;18(3):1072-8. Epub 2007 Dec 10.Synthesis of benzamide derivatives as TRPV1 antagonists.
Ref 529233Bioorg Med Chem Lett. 2008 Feb 1;18(3):1072-8. Epub 2007 Dec 10.Synthesis of benzamide derivatives as TRPV1 antagonists.

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