Drug General Information
Drug ID
D0XU4Y
Former ID
DNC011363
Drug Name
NSC-66209
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531262]
Structure
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2D MOL

3D MOL

Formula
C14H10O5
Canonical SMILES
CC1=C2C=C(C(=O)C=C2OC3=CC(=C(C=C13)O)O)O
InChI
1S/C14H10O5/c1-6-7-2-9(15)11(17)4-13(7)19-14-5-12(18)10(16)3-8(6)14/h2-5,15-17H,1H3
InChIKey
TZVNNUHRZXQCHM-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Induced myeloid leukemia cell differentiation protein Mcl-1 Target Info Inhibitor [531262]
Mannose-6-phosphate isomerase Target Info Inhibitor [531262]
KEGG Pathway PI3K-Akt signaling pathway
MicroRNAs in cancer
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Apoptosis signaling pathway
CCKR signaling map ST
Pathway Interaction Database E2F transcription factor network
Direct p53 effectors
IL6-mediated signaling events
HIF-1-alpha transcription factor network
WikiPathways Apoptosis
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
Apoptosis Modulation and Signaling
References
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).

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