Drug General Information
Drug ID	D0Y1UV
Former ID	DNC013657
Drug Name	1-(2,6-dimethoxy-4-methylphenyl)propan-2-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529336]
Structure		Download 2D MOL 3D MOL
Formula	C12H19NO2
Canonical SMILES	CC1=CC(=C(C(=C1)OC)CC(C)N)OC
InChI	1S/C12H19NO2/c1-8-5-11(14-3)10(7-9(2)13)12(6-8)15-4/h5-6,9H,7,13H2,1-4H3
InChIKey	CFFJUEYUTHKVMQ-UHFFFAOYSA-N
PubChem Compound ID	13753734
Target and Pathway
Target(s)	5-hydroxytryptamine 2A receptor	Target Info	Inhibitor	[529336]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and STAT3 Signaling
	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 529336	Bioorg Med Chem. 2008 Apr 15;16(8):4661-9. Epub 2008 Feb 14.The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands.
Ref 529336	Bioorg Med Chem. 2008 Apr 15;16(8):4661-9. Epub 2008 Feb 14.The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands.

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