Drug General Information
Drug ID	D0Y9HH
Former ID	DNC001325
Drug Name	SIB-1508Y
Drug Type	Small molecular drug
Indication	Parkinson's disease [ICD9: 332; ICD10:G20]		Terminated	[525768], [529637]
Structure		Download 2D MOL 3D MOL
Formula	C12H14N2
Canonical SMILES	CN1CCCC1C2=CN=CC(=C2)C#C
InChI	1S/C12H14N2/c1-3-10-7-11(9-13-8-10)12-5-4-6-14(12)2/h1,7-9,12H,4-6H2,2H3
InChIKey	NUPUDYKEEJNZRG-UHFFFAOYSA-N
CAS Number	CAS 192231-16-6
PubChem Compound ID	133106
PubChem Substance ID	15586747, 23920222, 29311101, 80336789, 103332400, 103949432, 104379014, 125646276, 128757112, 131302786, 136352593, 140370317, 162220085, 177749686, 179322555, 223944364, 227393619
Target and Pathway
Target(s)	Nicotinic ACh receptor alpha 4/beta 2	Target Info	Modulator
References
Ref 525768	Recombinant human receptors and functional assays in the discovery of altinicline (SIB-1508Y), a novel acetylcholine-gated ion channel (nAChR) agonist. Pharm Acta Helv. 2000 Mar;74(2-3):125-30.
Ref 529637	Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist. Brain Res. 2008 Oct 9;1234:16-24.

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