Drug General Information
Drug ID	D0YC1R
Former ID	DIB010712
Drug Name	BMS-520
Synonyms	BMS-520; S1P1 agonists (immunology); S1P1 agonists (immunology), Bristol-Myers Squibb
Indication	Immune disorder [ICD10:D80-D89]		Investigative	[543701]
Company	Bristol-Myers Squibb Co
Structure		Download 2D MOL 3D MOL
Canonical SMILES	FC(F)(c1c(c2ccccc2)noc1c1onc(c2ccc(CN3CC(C3)C(=O)O)cc2)<br />n1)F
Target and Pathway
Target(s)	Sphingosine 1-phosphate receptor 1	Target Info	Agonist	[543701]
KEGG Pathway	FoxO signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
NetPath Pathway	IL4 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
	IL2 Signaling Pathway
Pathway Interaction Database	Fc-epsilon receptor I signaling in mast cells
	S1P3 pathway
	S1P1 pathway
	Sphingosine 1-phosphate (S1P) pathway
	PDGFR-beta signaling pathway
Reactome	G alpha (i) signalling events
	Lysosphingolipid and LPA receptors
WikiPathways	Signal Transduction of S1P Receptor
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 543701	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).
Ref 543701	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 275).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.