Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0YH0N
|
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| Former ID |
DIB005117
|
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| Drug Name |
Metadoxine
|
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| Synonyms |
MG01CI; Metadoxine (oral sustained release, ADHD); Metadoxine (oral extended release, ADHD), Alcobra; Metadoxine (oral sustained release, ADHD), Alcobra
|
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| Drug Type |
Small molecular drug
|
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| Company |
Alcobra
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C13H18N2O6
|
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| Canonical SMILES |
c1(c(cnc(c1O)C)CO)CO.[C@H]1(CCC(=O)N1)C(=O)O
|
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| CAS Number |
CAS 74536-44-0
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Sodium- and chloride-dependent GABA transporter 1 | Target Info | Modulator | ||
| KEGG Pathway | GABAergic synapse | ||||
| WikiPathways | Monoamine Transport | ||||
| NRF2 pathway | |||||
| References | |||||
| Ref 524626 | ClinicalTrials.gov (NCT02051842) Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis. U.S. National Institutes of Health. | ||||
| Ref 531706 | Preliminary findings on the use of metadoxine for the treatment of alcohol dependence and alcoholic liver disease. Hum Psychopharmacol. 2011 Dec;26(8):554-9. | ||||
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