Drug Information
Drug General Information | |||||
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Drug ID |
D0Z1RV
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Former ID |
DAP000029
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Drug Name |
Clozapine
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Synonyms |
Asaleptin; CLOZARIL; Clorazil; Clozapin; Clozapina; Clozapinum; Fazaclo; Iprox; Leponex; Lepotex; Fazaclo ODT; C 6305; HF1854; Clopine (TN); Clozapina [INN-Spanish]; Clozapine(tautomer); Clozapinum [INN-Latin]; Clozaril (TN); Denzapine (TN); Fazaclo (TN); Froidir (TN); HF-1854; KS-1166; Klozapol (TN); LEX-123; LX 100-129; Leponex (TN); W-801; Zaponex (TN); Clozapine [USAN:INN:BAN]; Clozapine (JAN/USP/INN); 3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine; 8-Chloro-11-(4-methyl)-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo (b,e)(1,4)diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine; 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine; 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antipsychotic Agents
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Company |
Sandoz
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Structure |
Download2D MOL |
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Formula |
C18H19ClN4
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InChI |
InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
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InChIKey |
QZUDBNBUXVUHMW-UHFFFAOYSA-N
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CAS Number |
CAS 5786-21-0
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PubChem Compound ID | |||||
PubChem Substance ID |
9141, 631806, 855811, 4821023, 7847349, 7978980, 8004367, 8149634, 10321650, 10528074, 11110967, 11110968, 11113341, 11120316, 11120804, 11121292, 11121655, 11122135, 11335518, 11360757, 11362724, 11363013, 11365286, 11365575, 11367848, 11368137, 11370719, 11370720, 11373074, 11373449, 11374475, 11376010, 11376299, 11461729, 11466378, 11467498, 11484534, 11486076, 11488735, 11491643, 11492713, 11493953, 12013419, 14826474, 17404839, 24277892, 26612026, 26680236, 26747001, 26747002
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ChEBI ID |
ChEBI:3766
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SuperDrug ATC ID |
N05AH02
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SuperDrug CAS ID |
cas=005786210
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Target and Pathway | |||||
Target(s) | D(4) dopamine receptor | Target Info | Modulator | [556264] | |
References | |||||
Ref 536463 | The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31. | ||||
Ref 540514 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 38). |
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