Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1QW2
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| Drug Name |
2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[4-(1-methyl-piperidin-4-yloxy)-phenyl]-ethyl}-amide
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| Synonyms |
CHEMBL449096
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H34N6O2
|
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| Canonical SMILES |
CN1CCC(CC1)Oc2ccc(CCNC(=O)c3cnc(nc3NCC(C)(C)C)C#N)cc2
|
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| InChI |
InChI=1S/C25H34N6O2/c1-25(2,3)17-29-23-21(16-28-22(15-26)30-23)24(32)27-12-9-18-5-7-19(8-6-18)33-20-10-13-31(4)14-11-20/h5-8,16,20H,9-14,17H2,1-4H3,(H,27,32)(H,28,29,30)
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| InChIKey |
AKAUMTCIIOMDTI-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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