Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| mTOR --- AKT | N-(6-(6-Cyano-5-(4-methoxyphenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(4-tert-butylphenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(phenylsulfonamido)pyridin-3-yl)benzo-[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | (4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl){6-[(2R,3R)-2-(4-fluorophenyl)tetrahydrofuran-3-ylamino]-pyrazin-2-yl}methanone | Drug Info |
| mTOR --- AKT | trans-2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-4-methyl-6-(6-methylpyridin-3-yl)pteridin-7(8H)-one | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo[d]oxazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(5-(Benzo[d]thiazol-6-yl)-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(3-chlorophenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(6-(4-Methoxyphenylsulfonamido)pyrazin-2-yl)benzo-[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | (4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl){6-[(2R,3R)-2-(4-fluorophenyl)pyrrolidin-3-ylamino]pyrazin-2-yl}-methanone | Drug Info |
| mTOR --- AKT | 1-[(2R,3R)-3-[6-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]-pyrimidine-5-carbonyl)pyrazin-2-ylamino]-2-(4-fluorophenyl)-pyrrolidin-1-yl]ethanone | Drug Info |
| mTOR --- AKT | 2-amino-4-methyl-6-(6-methylpyridin-3-yl)-8-(tetrahydro-2H-pyran-4-yl)pteridin-7(8H)-one | Drug Info |
| mTOR --- AKT | N-(5-(2-Aminobenzo[d]oxazol-6-yl)-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide | Drug Info |
| mTOR --- AKT | (4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-{6-[(1R,2R)-2-(4-fluorophenyl)cyclopentylamino]pyrazin-2-yl}-methanone | Drug Info |
| mTOR --- AKT | N-(6-(2-(2-Fluorophenylsulfonamido)pyrimidin-4-yl)benzo-[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(2-(trifluoromethyl)phenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | (4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl){6-[(3S,4S)-4-(4-fluorophenyl)pyrrolidin-3-ylamino]pyrazin-2-yl}-methanone | Drug Info |
| mTOR --- AKT | N-(6-(3-(4-Methoxyphenylsulfonamido)phenyl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(2-(N-Ethyl-4-methoxyphenylsulfonamido)pyrimidin-4-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(4-(trifluoromethyl)phenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(4-methoxyphenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(2-(4-Methylphenylsulfonamido)pyrimidin-4-yl)benzo-[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(5-(4-Methoxyphenylsulfonamido)pyridin-3-yl)benzo-[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | trans-2-amino-8-(4-hydroxycyclohexyl)-4-methyl-6-(6-methylpyridin-3-yl)pteridin-7(8H)-one | Drug Info |
| mTOR --- AKT | N-(6-(5-(3-tert-Butylphenylsulfonamido)-6-chloropyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | 2-amino-4-methyl-6-(1H-pyrazol-3-yl)-8-(tetrahydro-2H-pyran-4-yl)pteridin-7(8H)-one | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(3-(trifluoromethyl)phenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(5-(2-Aminoimidazo[1,2-a]pyridin-6-yl)-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide | Drug Info |
| mTOR --- AKT | N-(5-(6-Chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)-1H-benzo[d]imidazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(4-chlorophenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(2-Chloro-5-(imidazo[1,2-b]pyridazin-6-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide | Drug Info |
| mTOR --- AKT | N-(6-(2-(4-Methoxyphenylsulfonamido)pyridin-4-yl)benzo-[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridin-2-yl)acetamide | Drug Info |
| mTOR --- AKT | 1-{(2R,3R)-3-[6-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]-pyrimidine-5-carbonyl)pyrazin-2-ylamino]-2-phenylpyrrolidin-1-yl}ethanone | Drug Info |
| mTOR --- AKT | N-(6-(6-Chloro-5-(2-chlorophenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide | Drug Info |
| mTOR --- AKT | N-(5-(2-aminobenzo[d]thiazol-6-yl)-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide | Drug Info |
| mTOR --- AKT | (2R,3R)-3-[6-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]-pyrimidine-5-carbonyl)pyrazin-2-ylamino]-2-(4-fluorophenyl)-pyrrolidine-1-carbaldehyde | Drug Info |
| mTOR --- AKT | trans-2-amino-8-((1r,4r)-4-hydroxycyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpteridin-7(8H)-one | Drug Info |
| mTOR --- AKT | (4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl){6-[(3S,4R)-4-(4-fluorophenyl)tetrahydrofuran-3-ylamino]-pyrazin-2-yl}methanone | Drug Info |
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