Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7NI8
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| Drug Name |
3-Chloro-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-benzamide
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| Synonyms |
CHEMBL519135
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H32ClN3O6S
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| Canonical SMILES |
CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC2(C)CCCC2)NC(=O)c3ccc(NS(=O)(=O)C)c(Cl)c3
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| InChI |
InChI=1S/C23H32ClN3O6S/c1-4-19-20(18(28)13-33-19)26-22(30)17(12-23(2)9-5-6-10-23)25-21(29)14-7-8-16(15(24)11-14)27-34(3,31)32/h7-8,11,17,19-20,27H,4-6,9-10,12-13H2,1-3H3,(H,25,29)(H,26,30)/t17-,19-,20+/m0/s1
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| InChIKey |
KQXQLJBYHQUENE-YSIASYRMSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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