Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXY1GX
|
||||
| Drug Name |
4'-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide
|
||||
| Synonyms |
CHEMBL198802
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H34N4O3
|
||||
| Canonical SMILES |
CN1CCC[C@H]1COc2ccc(cc2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
|
||||
| InChI |
InChI=1S/C28H34N4O3/c1-32-19-5-6-24(32)20-35-25-13-11-22(12-14-25)21-7-9-23(10-8-21)26(33)31-28(15-3-2-4-16-28)27(34)30-18-17-29/h7-14,24H,2-6,15-16,18-20H2,1H3,(H,30,34)(H,31,33)/t24-/m0/s1
|
||||
| InChIKey |
FSDBGHFCFNNHLR-DEOSSOPVSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.