Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX2O9B
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| Drug Name |
4-Benzenesulfonylamino-3-chloro-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-benzamide
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| Synonyms |
CHEMBL474059
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H34ClN3O6S
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| Canonical SMILES |
CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC2(C)CCCC2)NC(=O)c3ccc(NS(=O)(=O)c4ccccc4)c(Cl)c3
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| InChI |
InChI=1S/C28H34ClN3O6S/c1-3-24-25(23(33)17-38-24)31-27(35)22(16-28(2)13-7-8-14-28)30-26(34)18-11-12-21(20(29)15-18)32-39(36,37)19-9-5-4-6-10-19/h4-6,9-12,15,22,24-25,32H,3,7-8,13-14,16-17H2,1-2H3,(H,30,34)(H,31,35)/t22-,24-,25+/m0/s1
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| InChIKey |
PURTXMAIRNXPDK-ZKMPZPQNSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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