Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXN0D8
|
||||
| Drug Name |
6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile
|
||||
| Synonyms |
CHEMBL524619
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H20N6O
|
||||
| Canonical SMILES |
OCCCn1cnc2c(NCc3cccc(c3)c4ccccc4)nc(nc12)C#N
|
||||
| InChI |
InChI=1S/C22H20N6O/c23-13-19-26-21(20-22(27-19)28(15-25-20)10-5-11-29)24-14-16-6-4-9-18(12-16)17-7-2-1-3-8-17/h1-4,6-9,12,15,29H,5,10-11,14H2,(H,24,26,27)
|
||||
| InChIKey |
XPRAVWVEAFPXFC-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.