Drug Information

Drug General Information
Drug ID
DXV9L8
Drug Name
N-(7-Bromo-1-methoxy-6-phenyl-6H-benzo[c]chromen-8-yl)-methanesulfonamide
Synonyms
CHEMBL63768
Indication Discovery agent Investigative [1587926]
Formula
C21H18BrNO4S
Canonical SMILES
COc1cccc2OC(c3ccccc3)c4c(Br)c(NS(=O)(=O)C)ccc4c12
InChI
InChI=1S/C21H18BrNO4S/c1-26-16-9-6-10-17-18(16)14-11-12-15(23-28(2,24)25)20(22)19(14)21(27-17)13-7-4-3-5-8-13/h3-12,21,23H,1-2H3
InChIKey
AWPVKERKWQLOEG-UHFFFAOYSA-N
Target and Pathway
Target(s) Estrogen receptor Target Info [1587926]
Progesterone receptor Target Info [1587926]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Proteoglycans in cancerhsa04114:Oocyte meiosis
Progesterone-mediated oocyte maturation
NetPath Pathway FSH Signaling Pathway
EGFR1 Signaling Pathway
RANKL Signaling Pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Signaling events mediated by HDAC Class II
Plasma membrane estrogen receptor signaling
LKB1 signaling events
Regulation of Telomerase
ATF-2 transcription factor network
AP-1 transcription factor network
FOXM1 transcription factor network
Validated nuclear estrogen receptor alpha network
Signaling mediated by p38-alpha and p38-beta
FOXA1 transcription factor networkanthraxpathway:Cellular roles of Anthrax toxin
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
Nuclear Receptor transcription pathway
WikiPathways Estrogen signaling pathway
Nuclear Receptors Meta-Pathway
Estrogen Receptor Pathway
Signaling by ERBB4
JAK/STAT
Integrated Pancreatic Cancer Pathway
Leptin signaling pathway
miR-targeted genes in muscle cell - TarBase
Integrated Breast Cancer Pathway
Nuclear ReceptorsWP34:Ovarian Infertility Genes
Nuclear Receptors
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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