TTD | Drug: D0R2KL

Drug General Information
Drug ID	D0R2KL
Former ID	DIB020161
Drug Name	L-644,698
Synonyms	L644698; L-644698
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539179]
Structure		Download 2D MOL
Formula	C21H31NO4S
InChI	InChI=1S/C21H31NO4S/c1-2-3-4-7-18(23)13-14-22-19(24)15-27-20(22)8-5-6-16-9-11-17(12-10-16)21(25)26/h9-12,18,20,23H,2-8,13-15H2,1H3,(H,25,26)
InChIKey	NDAXAJCKSWCWQI-UHFFFAOYSA-N
PubChem Compound ID	9908595
PubChem Substance ID	14878722, 24189522, 45980258, 76885268, 85209130, 103341960, 128684775, 135650477, 224822390, 236043151
Target and Pathway
Target(s)	Prostaglandin D2 receptor	Target Info	Agonist	[525559]
KEGG Pathway	Neuroactive ligand-receptor interaction
Pathway Interaction Database	Thromboxane A2 receptor signaling
PathWhiz Pathway	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2
Reactome	Prostanoid ligand receptors
Reactome	G alpha (s) signalling events
WikiPathways	Prostaglandin Synthesis and Regulation
	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539179	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1879).
Ref 525559	A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor. Eur J Pharmacol. 1999 Jul 14;377(1):101-15.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information