Drug Information

Drug General Information
Drug ID
D0C1XB
Former ID
DIB018423
Drug Name
[3H]tiagabine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467924]
Structure
Download
2D MOL
Formula
C20H25NO2S2
InChI
InChI=1S/C20H25NO2S2/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23)/t16-/m1/s1
InChIKey
PBJUNZJWGZTSKL-MRXNPFEDSA-N
PubChem Compound ID
60648
PubChem Substance ID
9706, 7980788, 8186978, 14804309, 14926800, 26758048, 43118012, 46505560, 48416622, 50015636, 50510996, 53787330, 92723327, 93166176, 96025272, 103276854, 103946490, 104321287, 117542112, 126592912, 126617580, 128891680, 134337484, 135016989, 137002486, 142970946, 160847730, 160964245, 163418753, 163850077, 164814870, 172858819, 175268881, 178101399, 178101520, 179116918, 184545901, 210279817, 210282140, 223441308, 223554966, 223655564, 224165587, 226421082, 251916677, 251917916, 251970975, 252357544
Target and Pathway
Target(s) Sodium- and chloride-dependent GABA transporter 1 Target Info Inhibitor [543977]
KEGG Pathway GABAergic synapse
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
References
Ref 467924(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4685).
Ref 543977(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 929).

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