TTD | Drug: D0R1ZD

Drug General Information
Drug ID	D0R1ZD
Former ID	DIB019963
Drug Name	GSK575594A
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540939]
Structure		Download 2D MOL
Formula	C24H23F2N3O3S
InChI	InChI=1S/C24H23F2N3O3S/c1-33(31,32)19-7-8-20(16-2-4-17(25)5-3-16)21(15-19)24(30)29-12-10-28(11-13-29)23-9-6-18(27)14-22(23)26/h2-9,14-15H,10-13,27H2,1H3
InChIKey	DAPKZHQMEQRNPY-UHFFFAOYSA-N
PubChem Compound ID	59822766
PubChem Substance ID	141824995, 178102199, 224212434, 230818194, 248997349
Target and Pathway
Target(s)	G-protein coupled receptor 55	Target Info	Agonist	[531335]
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 540939	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5561).
Ref 531335	Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity glycine transporter subtype 1 inhibitor and GPR55 agonist. J Pharmacol Exp Ther. 2011 Apr;337(1):236-46.

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Drug Information