Drug General Information
Drug ID	D04UDE
Former ID	DNC013307
Drug Name	7-(4,6-dimethoxypyrimidin-2-yl)-2-methylquinoline
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528793]
Structure		Download 2D MOL 3D MOL
Formula	C16H15N3O2
Canonical SMILES	CC1=NC2=C(C=C1)C=CC(=C2)C3=NC(=CC(=N3)OC)OC
InChI	1S/C16H15N3O2/c1-10-4-5-11-6-7-12(8-13(11)17-10)16-18-14(20-2)9-15(19-16)21-3/h4-9H,1-3H3
InChIKey	BWVPGOLPFZULHO-UHFFFAOYSA-N
PubChem Compound ID	44427383
Target and Pathway
Target(s)	Metabotropic glutamate receptor 5	Target Info	Inhibitor	[528793]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Long-term potentiation
	Retrograde endocannabinoid signaling
	Glutamatergic synapse
	Huntington's disease
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Metabotropic glutamate receptor group III pathway
	Metabotropic glutamate receptor group I pathway
	Endogenous cannabinoid signaling
Reactome	G alpha (q) signalling events
	Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways	Hypothetical Network for Drug Addiction
	GPCRs, Class C Metabotropic glutamate, pheromone
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528793	Bioorg Med Chem Lett. 2007 Jun 1;17(11):2987-91. Epub 2007 Mar 24.Discovery of heterobicyclic templates for novel metabotropic glutamate receptor subtype 5 antagonists.
Ref 528793	Bioorg Med Chem Lett. 2007 Jun 1;17(11):2987-91. Epub 2007 Mar 24.Discovery of heterobicyclic templates for novel metabotropic glutamate receptor subtype 5 antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.