Drug Information

Drug General Information
Drug ID
D01PFN
Former ID
DNC005074
Drug Name
8-Cyclobutylmethoxy-quinolin-2-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527194]
Structure
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2D MOL

3D MOL
Formula
C14H16N2O
Canonical SMILES
C1CC(C1)COC2=CC=CC3=C2N=C(C=C3)N
InChI
1S/C14H16N2O/c15-13-8-7-11-5-2-6-12(14(11)16-13)17-9-10-3-1-4-10/h2,5-8,10H,1,3-4,9H2,(H2,15,16)
InChIKey
LOSCSSHHWRUJGD-UHFFFAOYSA-N
PubChem Compound ID
22254575
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [527194]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

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