Drug Information

Drug General Information
Drug ID
D0VR7W
Former ID
DAP000851
Drug Name
Gemifloxacin
Synonyms
Factiv; Factive; Gemifloxacin [INN]; Gemifloxacin mesilate; LB 20304; LB 20304a; SB 265805; Factiv (TN); Factive (TN); Gemifloxacin (INN); LB-20304; SB-265805; 7-(3-Aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid; 7-(3-Aminomethyl-4-methoxyimino-pyrrolidine-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)-naphthyridine-3-carboxylic acid; 7-[3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [536094]
Therapeutic Class
Antibiotics
Company
Oscient Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C18H20FN5O4
Canonical SMILES
CON=C1CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F
InChI
1S/C18H20FN5O4/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27)/b22-14+
InChIKey
ZRCVYEYHRGVLOC-HYARGMPZSA-N
CAS Number
CAS 175463-14-6
PubChem Compound ID
9571107
PubChem Substance ID
610685, 14878468, 23996711, 44709303, 46507905, 48395332, 50070532, 50071315, 50123382, 57372939, 79751939, 85305864, 85789646, 91613407, 96024705, 103165376, 104064190, 124766444, 126665045, 131302500, 134338130, 135029930, 137267488, 141952322, 152047100, 162263733, 163384560, 172861476, 175438039, 179150073, 223664023, 226504227, 238411063, 251890177, 251963973, 252358754
SuperDrug ATC ID
J01MA15
SuperDrug CAS ID
cas=175463146
Target and Pathway
Target(s) Bacterial DNA gyrase Target Info Modulator [556264]
Topoisomerase IV Target Info Modulator [556264]
References
Ref 536094Emerging drugs for bacterial urinary tract infections. Expert Opin Emerg Drugs. 2005 May;10(2):275-98.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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