Drug Information

Drug General Information
Drug ID
D0I7FK
Former ID
DNC005099
Drug Name
8-(3-Methyl-cyclohexyloxy)-quinolin-2-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527194]
Structure
Download
2D MOL

3D MOL
Formula
C16H20N2O
Canonical SMILES
CC1CCCC(C1)OC2=CC=CC3=C2N=C(C=C3)N
InChI
1S/C16H20N2O/c1-11-4-2-6-13(10-11)19-14-7-3-5-12-8-9-15(17)18-16(12)14/h3,5,7-9,11,13H,2,4,6,10H2,1H3,(H2,17,18)
InChIKey
AZGLOGDXDJFQFK-UHFFFAOYSA-N
PubChem Compound ID
10038053
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [527194]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.