Drug Information

Drug General Information
Drug ID
D0B5MP
Former ID
DAP000816
Drug Name
Aciclovir
Synonyms
Aciclovier; Aciclovirum; Activir; AcycloFoam; Acycloguanosine; Acyclovir; Avirax; Genvir; Hascovir; Maynar; Vipral; Virolex; Viropump; Virorax; Zovir; Zovirax; Aciclovirum [Latin]; Acyclovir Lauriad; Acyclovir [USAN]; A 4669; Aciclovirum [INN-Latin]; Acivir (TN); Acivirax (TN); Acyclovir (USP); Alti-Acyclovir; BW-248U; BW-248U74; Cyclovir (TN); DRG-0008; Herpex (TN); Wellcome-248U; Zovir (TN); Zovirax (TN); Zovirax Oral Acyclovir (ACV) Suspension; ACV & Pluronic F-68; Aciclovir (JAN/INN); Acyclovir & Pluronic F-68; B-LF& ACV; BW-248-U; W-248-U; Aciclovir, Acycloguanosine, Zovirax, Acyclovir; Acyclovir-side chain-2-3H; Bovine lactoferrin & 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; 2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one; 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; 2-Amino-9-(2-hydroxy-ethoxymethyl)-1,9-dihydro-purin-6-one; 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one; 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one; 2-amino-9-{[(2-hydroxyethyl)oxy]methyl}-1,9-dihydro-6H-purin-6-one; 6H-Purin-6-one,2-amino-1,9-dihydro-9-((2-hydroxyethoxy)mehtyl); 9-((2-Hydroxyethoxy)methyl)guanine; 9-(2-Hydroxyethoxy)methylguanine; 9-HYROXYETHOXYMETHYLGUANINE; 9-[(2-Hydroxyethoxy)-methyl]guanine; 9-[(2-Hydroxyethoxy)methyl]guanine; ACV
Drug Type
Small molecular drug
Indication Viral infections [ICD9: 054.0, 054.1, 054.2, 054.3, 075, 771.2, 052, 053; ICD10:B01, B02, A60, B00, B27, G05.1, P35.2] Approved [468061], [550782]
Therapeutic Class
Antiviral Agents
Company
GlaxoSmithKline
Structure
Download
2D MOL

3D MOL
Formula
C8H11N5O3
InChI
InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
InChIKey
MKUXAQIIEYXACX-UHFFFAOYSA-N
CAS Number
CAS 59277-89-3
PubChem Compound ID
2022
PubChem Substance ID
9029, 502278, 594925, 603044, 794369, 829893, 855732, 1916590, 5344000, 5344001, 6855606, 7847289, 7885662, 7978637, 8150001, 8151390, 10321108, 10589392, 11110742, 11110743, 11335360, 11360599, 11364633, 11367195, 11369757, 11372947, 11374028, 11377919, 11461571, 11466114, 11467234, 11485202, 11485687, 11489379, 11491689, 11492040, 11495553, 11528717, 12013356, 14773677, 15172245, 15220533, 17404601, 24278078, 24890562, 25621755, 26612492, 26679648, 26747423, 26747424
ChEBI ID
ChEBI:2453
SuperDrug ATC ID
D06BB03; J05AB01; S01AD03
SuperDrug CAS ID
cas=059277893
Target and Pathway
Target(s) DNA polymerase Target Info Modulator [556264]
References
Ref 468061(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4829).
Ref 550782Drug information of Aciclovir, 2008. eduDrugs.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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