Drug Information

Drug General Information
Drug ID
D07UDT
Former ID
DIB020180
Drug Name
L-798,106
Synonyms
L798106; L-798106
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539241]
Structure
Download
2D MOL
Formula
C27H22BrNO4S
InChI
InChI=1S/C27H22BrNO4S/c1-33-25-14-13-24(28)18-26(25)34(31,32)29-27(30)15-12-21-7-3-5-9-23(21)17-19-10-11-20-6-2-4-8-22(20)16-19/h2-16,18H,17H2,1H3,(H,29,30)/b15-12+
InChIKey
ODTKFNUPVBULRJ-NTCAYCPXSA-N
PubChem Compound ID
15551229
PubChem Substance ID
24775503, 28678562, 33319345, 99030149, 103506714, 104076296, 121360956, 135650500, 135698623, 164228057, 175612334, 204370378, 232353568, 232353578, 241376398, 252157210
Target and Pathway
Target(s) Prostaglandin E2 receptor EP3 subtype Target Info Antagonist [530182]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Regulation of lipolysis in adipocytes
Pathways in cancer
NetPath Pathway IL2 Signaling Pathway
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539241(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1941).
Ref 530182Dual modulation of urinary bladder activity and urine flow by prostanoid EP3 receptors in the conscious rat. Br J Pharmacol. 2009 Sep;158(1):372-81.

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