Drug Information

Drug General Information
Drug ID
D0V2IR
Former ID
DNC005093
Drug Name
8-(1-Ethyl-propoxy)-quinolin-2-ylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527194]
Structure
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2D MOL

3D MOL
Formula
C14H18N2O
Canonical SMILES
CCC(CC)OC1=CC=CC2=C1N=C(C=C2)N
InChI
1S/C14H18N2O/c1-3-11(4-2)17-12-7-5-6-10-8-9-13(15)16-14(10)12/h5-9,11H,3-4H2,1-2H3,(H2,15,16)
InChIKey
ZYSOQSQXCCTFTO-UHFFFAOYSA-N
PubChem Compound ID
10353807
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [527194]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

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