Drug General Information
Drug ID
D01ALG
Former ID
DPR000071
Drug Name
MCH antagonist
Indication Obesity [ICD9: 278; ICD10:E66] Preclinical [536122]
Company
Argenta
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Antagonist [536122]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

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