Drug Information

Drug General Information
Drug ID
D0S3UR
Former ID
DIB020728
Drug Name
PIP3
Synonyms
phosphatidylinositol-3,4,5-trisphosphate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539493]
Structure
Download
2D MOL
Formula
C47H86O22P4
InChI
InChI=1S/C12H24O22P4/c1-4(13)29-6(30-5(2)14)3-28-38(26,27)34-9-7(15)10(31-35(17,18)19)12(33-37(23,24)25)11(8(9)16)32-36(20,21)22/h6-12,15-16H,3H2,1-2H3,(H,26,27)(H2,17,18,19)(H2,20,21,22)(H2,23,24,25)/t7-,8-,9-,10+,11-,12-/m0/s1
InChIKey
RQQIRMLGKSPXSE-UQPICLANSA-N
PubChem Compound ID
53480352
Target and Pathway
Target(s) CNGA2 Target Info Inhibitor (gating inhibitor) [528468]
References
Ref 539493(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2353).
Ref 528468Interplay between PIP3 and calmodulin regulation of olfactory cyclic nucleotide-gated channels. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15635-40. Epub 2006 Oct 10.

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