Drug General Information
Drug ID	D0L1IB
Former ID	DNC014096
Drug Name	(S)-3-(azetidin-2-ylmethoxy)-2-fluoropyridine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530178]
Structure		Download 2D MOL 3D MOL
Formula	C9H11FN2O
Canonical SMILES	C1CNC1COC2=C(N=CC=C2)F
InChI	1S/C9H11FN2O/c10-9-8(2-1-4-12-9)13-6-7-3-5-11-7/h1-2,4,7,11H,3,5-6H2/t7-/m0/s1
InChIKey	GVOOYVOZPRROMP-ZETCQYMHSA-N
PubChem Compound ID	10241442
Target and Pathway
Target(s)	Neuronal acetylcholinereceptor subunit alpha-2	Target Info	Inhibitor	[530178]
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Nicotinic acetylcholine receptor signaling pathway
Reactome	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
	Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 530178	Bioorg Med Chem. 2009 Jul 1;17(13):4367-77. Epub 2009 May 15.Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography.
Ref 530178	Bioorg Med Chem. 2009 Jul 1;17(13):4367-77. Epub 2009 May 15.Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography.

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