Drug General Information
Drug ID
D06PII
Former ID
DNC003384
Drug Name
SULTHIAME
Drug Type
Small molecular drug
Indication Discovery agent Phase 3 [522025]
Structure
Download
2D MOL

3D MOL

Formula
C10H14N2O4S2
Canonical SMILES
C1CCS(=O)(=O)N(C1)C2=CC=C(C=C2)S(=O)(=O)N
InChI
1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16)
InChIKey
HMHVCUVYZFYAJI-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
N03AX03
Target and Pathway
Target(s) Carbonic anhydrase II Target Info Inhibitor [551374]
KEGG Pathway Nitrogen metabolism
Proximal tubule bicarbonate reclamation
Collecting duct acid secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
NetPath Pathway IL4 Signaling Pathway
EGFR1 Signaling Pathway
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxide
WikiPathways Reversible Hydration of Carbon Dioxide
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 522025ClinicalTrials.gov (NCT00471744) HEAD-Study Optimizing the Treatment of Children With BECTS. U.S. National Institutes of Health.
Ref 551374The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

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