Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0HI2N
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| Former ID |
DNC013174
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| Drug Name |
D[Cha4,Dab8]VP
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| Indication | Discovery agent | Investigative | [539387] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C48H67N11O11S2
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| Canonical SMILES |
C1CCC(CC1)CC2C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)NC(C(=O)<br />N2)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N5CCCC5C(=O)NC(CCN<br />)C(=O)NCC(=O)N)CC(=O)N
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| InChI |
1S/C48H67N11O11S2/c49-19-17-32(42(64)52-26-40(51)62)54-47(69)38-12-7-20-59(38)48(70)37-27-72-71-21-18-41(63)53-33(24-30-13-15-31(60)16-14-30)43(65)55-34(22-28-8-3-1-4-9-28)44(66)56-35(23-29-10-5-2-6-11-29)45(67)57-36(25-39(50)61)46(68)58-37/h1,3-4,8-9,13-16,29,32-38,60H,2,5-7,10-12,17-27,49H2,(H2,50,61)(H2,51,62)(H,52,64)(H,53,63)(H,54,69)(H,55,65)(H,56,66)(H,57,67)(H,58,68)/t32-,33-,34-,35-,36-,37-,38-/m0/s1
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| InChIKey |
DPVYQFBOSXXNLG-CXWHUAPYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Vasopressin V1b receptor | Target Info | Inhibitor | [528674] | |
| Oxytocin receptor | Target Info | Inhibitor | [528674] | ||
| Vasopressin V1a receptor | Target Info | Inhibitor | [528674] | ||
| Vasopressin V2 receptor | Target Info | Inhibitor | [528674] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Vascular smooth muscle contractionhsa04020:Calcium signaling pathway | |||||
| cAMP signaling pathway | |||||
| Oxytocin signaling pathwayhsa04020:Calcium signaling pathway | |||||
| Vascular smooth muscle contractionhsa04080:Neuroactive ligand-receptor interaction | |||||
| Vasopressin-regulated water reabsorption | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| PANTHER Pathway | Oxytocin receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Arf6 trafficking events | ||||
| PathWhiz Pathway | Vasopressin Regulation of Water Homeostasis | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
| Myometrial Relaxation and Contraction Pathways | |||||
| Oxytocin signaling | |||||
| Regulation of Water Balance by Renal Aquaporins | |||||
| GPCR downstream signaling | |||||
| References | |||||
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