Drug Information

Drug General Information
Drug ID
D0I7AL
Former ID
DIB018085
Drug Name
(R)-EF-1520
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541649]
Structure
Download
2D MOL
Formula
C22H26N2O2S2
InChI
InChI=1S/C22H26N2O2S2/c1-14-9-12-27-20(14)16(21-15(2)10-13-28-21)6-5-11-24(3)17-7-4-8-18-19(17)22(25)23-26-18/h6,9-10,12-13,17H,4-5,7-8,11H2,1-3H3,(H,23,25)/t17-/m1/s1
InChIKey
CUESOMOCKVRNIW-QGZVFWFLSA-N
PubChem Compound ID
53321930
PubChem Substance ID
124966729, 127678600, 178103126
Target and Pathway
Target(s) BGT1 Target Info Inhibitor [543978]
Sodium- and chloride-dependent GABA transporter 1 Target Info Inhibitor [543977]
KEGG Pathway GABAergic synapse
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
References
Ref 541649(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6512).
Ref 543977(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 929).
Ref 543978(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 932).

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