Drug General Information
Drug ID	D03SEC
Former ID	DNC005073
Drug Name	8-Butoxy-quinolin-2-ylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527194]
Structure		Download 2D MOL 3D MOL
Formula	C13H16N2O
Canonical SMILES	CCCCOC1=CC=CC2=C1N=C(C=C2)N
InChI	1S/C13H16N2O/c1-2-3-9-16-11-6-4-5-10-7-8-12(14)15-13(10)11/h4-8H,2-3,9H2,1H3,(H2,14,15)
InChIKey	RANHBKGFWNIVKN-UHFFFAOYSA-N
PubChem Compound ID	10443307
Target and Pathway
Target(s)	Melanin-concentrating hormone receptor 1	Target Info	Inhibitor	[527194]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527194	Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194	Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

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