Drug Information

Drug General Information
Drug ID
D06GWF
Former ID
DAP000646
Drug Name
Valganciclovir
Synonyms
Cymeval; RS 79070; RO1079070/194; Valcyte (TN); Valganciclovir (INN); Valganciclovir (Oral); Valganciclovir [INN:BAN]; L-Valine, ester with ganciclovir; [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] (2S)-2-amino-3-methylbutanoate; L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-3-hydroxypropyl ester; 5-Amino-3-[1-(hydroxymethyl)-2-(L-valyloxy)ethoxymethyl]-6,7-dihydro-3H-imidazo[4,5-d]pyrimidin-7-one
Drug Type
Small molecular drug
Indication Viral infections [ICD9: 054.0, 054.1, 054.2, 054.3, 075, 771.2, 052, 053; ICD10:B01, B02, A60, B00, B27, G05.1, P35.2] Approved [467957], [536361]
Therapeutic Class
Antiviral Agents
Company
Roche Laboratories Inc
Structure
Download
2D MOL

3D MOL
Formula
C14H22N6O5
InChI
InChI=1S/C14H22N6O5/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22)/t8?,9-/m0/s1
InChIKey
WPVFJKSGQUFQAP-GKAPJAKFSA-N
CAS Number
CAS 175865-60-8
PubChem Compound ID
64147
PubChem Substance ID
615108, 7980872, 14852135, 14852136, 15916891, 16292870, 16867892, 43121054, 46505524, 47205808, 50064546, 50113281, 50647485, 57315041, 91616537, 92251598, 104330216, 117576840, 123099361, 126681567, 129616655, 134337936, 135022474, 135611114, 137260967, 141634799, 142044094, 152035502, 152105972, 160647806, 160964847, 162205159, 163621140, 164830911, 172086164, 178101427, 184546497, 184823771, 223661894, 226416180, 237715327, 251916051, 251917399
SuperDrug ATC ID
J05AB14
SuperDrug CAS ID
cas=175865608
Target and Pathway
Target(s) DNA polymerase Target Info Inhibitor [537140]
References
Ref 467957(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4716).
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 537140Drug targets in cytomegalovirus infection. Infect Disord Drug Targets. 2009 Apr;9(2):201-22.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.