Drug General Information
Drug ID
D03ZHE
Former ID
DIB013570
Drug Name
MDX-070
Drug Type
Antibody
Indication Prostate cancer [ICD9: 185; ICD10:C61] Discontinued in Phase 2 [547384]
Company
Medarex
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info [544341]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 547384Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015769)
Ref 544341Nanoparticles for Improving Cancer Diagnosis. Mater Sci Eng R Rep. 2013 March; 74(3): 35-69.

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