Drug Information
Drug General Information | |||||
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Drug ID |
D0X4MC
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Former ID |
DCL000043
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Drug Name |
AMG 076
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Drug Type |
Small molecular drug
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Indication | Obesity [ICD9: 278; ICD10:E66] | Discontinued in Phase 1 | [547852] | ||
Company |
Amgen
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Structure |
Download2D MOL |
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Formula |
C26H33F3N2O2
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Canonical SMILES |
CC1C2CN(CCC2CC3=C1C4=C(N3)C=CC(=C4)C(F)(F)F)CCC5(CCCCC5<br />)C(=O)O
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InChI |
1S/C26H33F3N2O2/c1-16-20-15-31(12-10-25(24(32)33)8-3-2-4-9-25)11-7-17(20)13-22-23(16)19-14-18(26(27,28)29)5-6-21(19)30-22/h5-6,14,16-17,20,30H,2-4,7-13,15H2,1H3,(H,32,33)/t16-,17-,20-/m1/s1
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InChIKey |
WAOZNBXSEVIAGX-MBOZVWFJSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
ChEBI ID |
ChEBI:43362
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Target and Pathway | |||||
Target(s) | Melanin-concentrating hormone receptor 1 | Target Info | Antagonist | [536531] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
References |
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