Drug Information

Drug General Information
Drug ID
D0U7WN
Former ID
DIB005148
Drug Name
A-80987
Synonyms
ABT-987
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Discontinued in Phase 1 [545217]
Company
Abbott Laboratories
Structure
Download
2D MOL

3D MOL
Formula
C37H43N5O6
Canonical SMILES
C(=O)(N[C@H]([C@H](C[C@@H](NC(=O)OCc1cnccc1)Cc1ccccc1)O<br />)Cc1ccccc1)[C@@H](NC(=O)OCc1ncccc1)C(C)C
CAS Number
CAS 144141-97-9
PubChem Compound ID
461207
Target and Pathway
Target(s) HIV protease Target Info Inhibitor [534168]
References
Ref 545217Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002482)
Ref 534168Human serum alpha 1 acid glycoprotein reduces uptake, intracellular concentration, and antiviral activity of A-80987, an inhibitor of the human immunodeficiency virus type 1 protease. Antimicrob Agents Chemother. 1996 Jun;40(6):1491-7.

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